Trelagliptin succinate

SKU: orb1305768

Description

Trelagliptin succinate (SYR-472 succinate) is a long-acting DPP-4 inhibitor developed for type 2 diabetes management. It is used in research to study incretin hormone stabilization and glycemic control in both in vitro enzymatic assays and in vivo diabetic animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1029877-94-8
• MW: 475.47
• Purity: >99.99% (May vary between batches)
• Formula: C₂₂H₂₆FN₅O₆
• SMILES: Cn1c(=O)cc(n(c1=O)Cc1c(ccc(c1)F)C#N)N1CCC[C@H](C1)N.C(CC(=O)O)C(=O)O
• Target: DPP-4,Proteasome
• Solubility: DMSO:55 mg/mL (115.68 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.21 mM)

Bioactivity

• Target IC50:
  DPP4:4 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Diabete, Dipeptidyl Peptidase, DPP, DPP4, DPP-4, Anti-diabetic, inhibit, Inhibitor, mellitus, glycemic, Zafatek, SYR472, SYR-472, SYR472 Succinate, SYR-472 Succinate, SYR-472 succinate, SYR 472, SYR 472 Succinate, Trelagliptin, Trelagliptin succinate, Trelagliptin Succinate

Compound Identifiers

PubChem CID

44183569