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    TOX3 Antibody

    TOX3 Antibody

    Catalog Number: orb749531

    DispatchUsually dispatched within 5-10 working days
    $ 764.00
    Catalog Numberorb749531
    CategoryAntibodies
    DescriptionIt recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
    Species/HostMouse
    ClonalityMonoclonal
    Clone NumberTOX3/1123
    Tested applicationsWB
    ReactivityHuman
    IsotypeMouse IgG2b, kappa
    ImmunogenA recombinant fragment (139 amino acid residues around aa 200-400) from the human protein was used as the immunogen for the TOX3 antibody.
    Dilution rangeWestern blot: 1-2ug/ml
    PurityProtein G affinity chromatography
    ConjugationUnconjugated
    Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
    Hazard InformationThis TOX3 antibody is available for research use only.
    UniProt IDO15405
    StorageStore the TOX3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
    Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
    NoteFor research use only
    Application notesOptimal dilution of the TOX3 antibody should be determined by the researcher.
    Expiration Date12 months from date of receipt.
    • TOX3 Antibody [orb1264434]

      FC,  IHC-P,  WB

      Human, Mouse

      Rabbit

      Polyclonal

      Unconjugated

      400 μl
    • TOX3 antibody [orb35109]

      FC,  IHC-P,  WB

      Human, Mouse

      Rabbit

      Polyclonal

      Unconjugated

      80 μl
    • TOX3 Antibody [orb1252546]

      FC,  IF,  IHC-P,  WB

      Human

      Mouse

      Monoclonal

      Unconjugated

      100 μg
    • TOX3 antibody [orb44355]

      ELISA,  IF,  IHC,  WB

      Human, Mouse

      Rabbit

      Polyclonal

      Unconjugated

      100 μg, 50 μg
    • TOX3 antibody (HRP) [orb44356]

      ELISA

      Human

      Rabbit

      Polyclonal

      HRP

      100 μg, 50 μg
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