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Tosatoxumab Antibody

Tosatoxumab Antibody

Catalog Number: orb1980471

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Catalog Numberorb1980471
CategoryAntibodies
DescriptionTosatoxumab (AR-301; KBSA301), a human immunoglobulin G1 monoclonal antibody, specifically targets and neutralizes S. aureus alpha-toxin (alpha-hemolysin; Hla) by binding to its N-terminal epitope. This interaction blocks the toxin's ability to form functional pore oligomers, crucial for its pathogenic activity. As a result, Tosatoxumab offers promising potential as an adjunctive passive immunotherapy alongside conventional antibiotics for S. aureus pneumonia [1] [2].
TargetTosatoxumab
ClonalityMonoclonal
ConjugationUnconjugated
Purity98.00%
CAS Number1374419-41-6
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
NoteFor research use only
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    ELISA

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    Mouse

    Monoclonal

    Unconjugated

    100 μg, 1 mg
  • Anti-Staphylococcus aureus α toxin Reference Antibody (Tosatoxumab) [orb1817812]

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    100 mg