TOPORS (C) Antibody, Rabbit Polyclonal

• Catalog Number: orb67252
• Category: Antibodies
• Description: Rabbit polyclonal to TOPORS.TOPORS functions as an E3 ubiquitin-protein ligase and an E3 SUMO1-protein ligase. It is a probabletumor suppressor involved in cell growth, cell proliferation and apoptosis. TOPORS regulatesp53/TP53 stability through ubiquitin-dependent degradation. It may regulate chromatin modificationthrough sumoylation of several chromatin modification-associated proteins. It may be involved in DNAdamage-induced cell death through IKBKE sumoylation. Defects in TOPORS are the cause of retinitispigmentosa type 31 P31).
• Clonality: Polyclonal
• Species/Host: Rabbit
• Conjugation: Unconjugated
• Reactivity: Human
• Buffer/Preservatives: 0.01% NaN3
• Purity: Affinity purification
• Immunogen: C-terminal region of human TOPORS
• UniProt ID: Q9NS56
• MW: 119
• Tested applications: WB
• Dilution range: WB:1:500-1:1000
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: anti-TOPORS antibody,anti-E3 ubiquitinprotein liga
• Research Area: Cancer, DNA Damage, Epigenetics
• Note: For research use only

Western blot analysis of total cell extracts from human Hela using TOPORS antibody