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Topoisomerase I inhibitor 16

SKU: orb3133991

Description

Topoisomerase I inhibitor 21 (Compound 3e) inhibits Topoisomerase I by stabilizing the enzyme-DNA complex. It exhibits antiproliferative activity in 39 types of human cancer cells (JFCR39), with an average GI50 of 39 nM.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

FormulaC27H27N3O4
TargetTopoisomerase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information