Ganoderic acid X

SKU: orb1682524

Description

Ganoderic acid X is a potent Mdm2 inhibitor (K(i) = 16 nM) with demonstrated anticancer activity. It functions by inhibiting topoisomerase activity and inducing apoptosis, as shown in in vitro studies. This compound is a valuable research tool for investigating p53-mediated pathways and novel chemotherapeutic strategies.

Research Area

Cell Biology, Molecular Biology, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 86377-53-9
• MW: 512.731
• Formula: C₃₂H₄₈O₅
• SMILES: [H][C@@]1(C[C@H](OC(C)=O)[C@@]2(C)C3=CC[C@@]4([H])C(C)(C)[C@H](O)CC[C@]4(C)C3=CC[C@]12C)[C@H](C)CC\C=C(/C)C(O)=O
• Target: MAPK,Mdm2,ERK,Apoptosis,Caspase,JNK,p53,Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

101600075