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Topoisomerase I inhibitor 14

SKU: orb3133148

Description

Topoisomerase I inhibitor 14 (Compound 4h) acts as an inhibitor of topoisomerase I. It suppresses the proliferation of A549 and C6 cells, with IC50 values of 4.56 μM and 13.17 μM, respectively. The compound shows no significant toxicity towards healthy NIH3T3 cells (IC50 of 74.44 μM) and demonstrates anticancer activity.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

FormulaC28H29N9O2S
TargetTopoisomerase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information