TX-2552

SKU: orb2664302

Description

TX-2552 is a potent and orally bioavailable TDP1 inhibitor (IC50 = 0.62 µM). It synergizes with topoisomerase I poisons like topotecan, enhancing DNA damage and antitumor efficacy in both cellular assays and murine cancer models, supporting its investigation in oncology research.

Key Properties

• CAS Number: 2446767-14-0
• MW: 392.46
• Formula: C₂₅H₂₅FO₃
• SMILES: O=C1C=C(C=2C(=CC(OC/C=C(/CCC=C(C)C)\C)=CC2)O1)C3=CC=C(F)C=C3

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

154699172