TMPyP4 tosylate

SKU: orb1309001

Description

TMPyP4 tosylate (TMP 1363) is a quadruplex-binding ligand that inhibits telomerase activity. It has demonstrated antitumor effects in osteosarcoma cell lines in vitro and serves as a research tool for studying G-quadruplex biology and cancer therapeutics.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology, Neuroscience

Key Properties

• CAS Number: 36951-72-1
• MW: 1363.6
• Purity: 99.85% (May vary between batches)
• Formula: C₇₂H₆₆N₈O₁₂S₄
• SMILES: Cc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.CN1CC=C(C=C1)c1c2ccc(n2)c(C2=CCN(C)C=C2)c2ccc([nH]2)c(C2=CCN(C)C=C2)c2ccc(n2)c(C2=CCN(C)C=C2)c2ccc1[nH]2
• Target: DNA/RNA Synthesis,SARS-CoV,Cholinesterase (ChE),Telomerase
• Solubility: H2O:6.2 mg/mL (4.55 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (0.73 mM);DMSO:18.33 mg/mL (13.44 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TMP1363, TMP-1363, TMP 1363, TMPyP4 tosylate, TMPyP-4, TMPyP4 Tosylate, TMPyP-4 tosylate, TMPyP4, TMPyP 4, Telomerase, RNA Synthesis, RNASynthesis, inhibit, Inhibitor, G-quadruplexe, G-quadruplex, DNA Synthesis, DNASynthesis

Compound Identifiers

PubChem CID

160602182