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Catalog Number | orb131753 |
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Category | Antibodies |
Description | Rabbit polyclonal to TLR9. Toll-like receptor 9 (TLR9) is a single-pass type I membrane protein belonging to the Toll-like receptor family. TLR9 is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidinephosphate-guanosine (CpG) dinucleotides. TLR9 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Furthermore, TLR9 controls lymphocyte response to Helicobacter infection. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human |
Immunogen | C-terminal region of human TLR9 |
Concentration | 100 μg/ml BSA |
Dilution range | WB:1:1000-1:3000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 116 |
UniProt ID | Q9NR96 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti Toll-like receptor 9 antibody, anti CD289 ant Read more... |
Note | For research use only |
Application notes | < strong>WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications. < br>< strong>Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human TLR9. |
Expiration Date | 12 months from date of receipt. |