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TLR7 agonist 20

TLR7 agonist 20

Catalog Number: orb2564387

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Catalog Numberorb2564387
CategorySmall Molecules
DescriptionTLR7 agonist20 (compound 23) is an imidazoquinoline analogue. It acts as a potent and specific TLR7 agonist with an EC50 value of 0.23 μM for hTLR7. This compound exhibits strong adjuvant activity on spike antibody levels and induces a robust T helper cell 1 (Th1) response, increasing IgG2b and IgG2c alongside IgG1.
Purity98.00%
MW360.45
CAS Number3029695-00-6
FormulaC22H24N4O
SMILESOCC1=CC=C(C=C1)CN2C(=NC=3C(=NC=4C=CC=CC4C32)N)CCCC
Storage-20°C
NoteFor research use only
  • TLR7 agonist 20 hydrochloride [orb2663589]

    98.00%

    396.91

    C22H25ClN4O

    10 mg, 50 mg
  • TLR7 agonist 17 [orb2565154]

    98.00%

    2410517-32-5

    483.61

    C25H37N7O3

    50 mg, 10 mg
  • TLR7 agonist 12 [orb1982209]

    98.00%

    2389988-47-8

    385.33

    C14H19N5O8

    50 mg, 5 mg