Tiparp Antibody (N-term)

SKU: orb38808

Description

Rabbit polyclonal antibody to Tiparp is also known as DDF1, PARP 1, is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor antibody, anti-repeated rounds of ADP-ribosylation leads to the formation of poly (ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.

Research Area

Epigenetics

Images & Validation

• Tested Applications: IHC-P, WB
• Dilution range: IHC-P: 1:10-50, WB: 1:1000
• Reactivity: Mouse

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: RB14171
• Immunogen: Synthetic Peptide
• Target: Tiparp
• Molecular Weight: 75901
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Disclaimer: For research use only

Alternative Names

Anti-TCDD-inducible poly [ADP-ribose] polymerase antibody, anti-EC 2.4.2.30 antibody, anti-Poly [ADP-ribose] polymerase 7 antibody, anti-PARP-7 antibody, anti-TIPARP antibody, anti-PARP7 antibody

Tiparp Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35 ug/lane). This demonstrates the Tiparp antibody detected the Tiparp protein (arrow).

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with Tiparp antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Quick Database Links

Gene Symbol

Tiparp

UniProt

Q8C1B2

RefSeq (Protein):NP_849223.2