Timolumab Antibody

SKU: orb1980611

Description

Timolumab (BTT 1023) is a fully human monoclonal antibody targeting Vascular Adhesion Protein-1 (VAP-1). It has demonstrated anti-fibrotic effects in murine liver injury models, making it a relevant research tool for investigating primary sclerosing cholangitis (PSC) and related fibrotic diseases.

Key Properties

• CAS Number: 1073538-99-4
• MW: 144.44 kDa
• Purity: 95.00%
• Target: Others

Bioactivity

• In Vitro:
  Timolumab binds to human VAP-1, thereby inhibiting it from functioning as an adhesion molecule. It also recognizes VAP-1 from other primates and rabbits, but does not cross-react to VAP-1 from rats and mice.

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BTT1023, BTT 1023, BTT 1023; Anti-Human AOC3 Recombinant Antibody

Quick Database Links

Gene Symbol

Others