Thiostrepton

SKU: orb1307777

Description

Thiostrepton is a cyclic peptide antibiotic derived from Streptomyces with activity against Gram-positive bacteria. It has been used in veterinary applications, including mastitis treatment, and serves as a research tool for studying bacterial translation and ribosome function in both in vitro and in vivo models.

Research Area

Cell Biology

Key Properties

• CAS Number: 1393-48-2
• MW: 1664.91
• Purity: >98%
• Formula: C₇₂H₈₅N₁₉O₁₈S₅
• SMILES: CC[C@H](C)[C@@H]1N[C@@H]2C=Cc3c(cc(nc3[C@H]2O)C(=O)O[C@H](C)[C@@H]2NC(=O)c3csc(n3)[C@@H](NC(=O)[C@H]3CSC(=N3)\C(NC(=O)[C@@H](NC(=O)c3csc(n3)[C@]3(CCC(=N[C@@H]3c3csc2n3)c2nc(cs2)C(=O)NC(=C)C(=O)NC(=C)C(N)=O)NC(=O)[C@H](C)NC(=O)C(=C)NC(=O)[C@H](C)NC1=O)[C@@H](C)O)=C\C)C(C)(O)[C@@H](C)O)[C@H](C)O
• Target: Antibiotic
• Solubility: Soluble in DMSO (up to 15 mg/ml), or in Chloroform (up to 5 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Thiactin, Thiostrepton, RNA Synthesis, RNASynthesis, Inhibitor, inhibit, Antibiotic, Bryamycin, Bacterial, Alaninamide, DNA synthesis, DNA Synthesis, DNASynthesis

Compound Identifiers

PubChem CID

146681945