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Thalidomide-4-OH

SKU: orb1299530

Description

Thalidomide-4-OH

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number5054-59-1
MW274.229
Purity99.79% (May vary between batches)
FormulaC13H10N2O5
SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3O)=O
TargetLigands for E3 Ligase,Autophagy,Apoptosis
Solubility10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (12.03 mM);DMSO:30 mg/mL (109.4 mM)

Bioactivity

In Vitro
Thalidomide-OH has weak anti-angiogenic activity. Thalidomide-OH does not have any anti-proliferative effect against the breast or neuroblastoma cells, but do possess appreciable anti-proliferative activity against the endothelial cells.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Ligand for E3 Ligase, LigandforE3Ligase, Ligands for E3 Ligase, Inhibitor, E3 ligase Ligand 2, E3 ligase-recruiting Moiety, Cereblon, Cereblon ligand2, Cereblon ligand-2, Cereblon ligand 2, Thalidomide4OH, Thalidomide-4-OH, Thalidomide 4 OH

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Key Properties

No computed properties available.

Protocol Information

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500 mg
$ 70.00
DispatchUsually dispatched within 5-10 working days
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