Thalidomide-4-OH-C11-OH

SKU: orb3027458

Description

Thalidomide-4-OH-C11-OH is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), comprising Thalidomide-4-OH and the corresponding linker. Thalidomide-4-OH-C11-OH acts as a Cereblon ligand to recruit CRBN protein and serves as a key intermediate for synthesizing complete PROTAC molecules, such as PROTAC GPX4 degrader-4.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3071165-50-6
• MW: 444.52
• Formula: C₂₄H₃₂N₂O₆
• SMILES: O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCCCCCCCCCCO)C3C2=O)CC1
• Target: E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

E3 Ligase Ligand-Linker Conjugates