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TGFβRI-IN-3

SKU: orb2900258

Description

TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology.

Images & Validation

Key Properties

CAS Number2763602-67-9
MW465.57
Purity>98% (HPLC)
FormulaC28H23N3O2S
SMILESN(C=1C2=C(C=C(C=C2)C3=CC=C(S(C)(=O)=O)C=C3)N=CC1)C=4C=C(N=CC4)C5=CC(C)=CC=C5
SolubilityIn Vitro: DMSO : 50 mg/mL (107.40 mM; Ultrasonic (<60°C)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • TGFβRI-IN-3 [orb1298043]

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    C28H23N3O2S

    1 mg, 5 mg, 50 mg, 100 mg, 10 mg, 25 mg, 500 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

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2 mg
$ 200.00
5 mg
$ 290.00
10 mg
$ 450.00
25 mg
$ 840.00
50 mg
$ 1,300.00
100 mg
$ 1,810.00
500 mg
$ 3,590.00