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TBA-354

SKU: orb1226660

Description

TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv; maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates, demonstrates superior potency and pharmacokinetic profile compared with PA-824, 5 to 10 times more potent than PA-824.Bacterial Infection Phase 1 Clinical.

Images & Validation

Key Properties

CAS Number1257426-19-9
MW436.3414
Purity>98% (HPLC)
FormulaC19H15F3N4O5
SMILESO=[N+](C1=CN2C(OC[C@@H](OCC3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)N=C3)C2)=N1)[O-]
TargetAntibacterial
SolubilityDMSO: ≥ 46 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TBA354

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  • TBA-354 [orb1303965]

    99.35% (May vary between batches)

    1257426-19-9

    436.34

    C19H15F3N4O5

    10 mg, 50 mg, 100 mg, 25 mg, 1 ml x 10 mM (in DMSO), 200 mg
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Protocol Information

Available Sizes

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500 mg
200 mg
2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 210.00
25 mg
$ 360.00
50 mg
$ 580.00
100 mg
$ 860.00