Tavaborole

SKU: orb1304296

Description

Tavaborole (Kerydin) is a boron-based antifungal compound effective against a broad range of filamentous fungi, including molds and yeasts. It is utilized in research for both in vitro susceptibility testing and in vivo models of fungal infection, supporting studies in microbiology and antifungal drug development.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 174671-46-6
• MW: 151.93
• Purity: 99.94% (May vary between batches)
• Formula: C₇H₆BFO₂
• SMILES: OB1C=2C(CO1)=CC(F)=CC2
• Target: Antifungal,Antibiotic
• Solubility: DMSO:250 mg/mL (1645.49 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (13.16 mM)

Bioactivity

• In Vitro:
  AN-2690 demonstrates a significant enhancement in efficacy, exhibiting an 8-fold increase in activity against both C. neoformans and A. fumigatus. It effectively inhibits cells expressing GlLeuRS-D444A, yet shows no inhibitory effect on cells expressing GlLeuRS or GlLeuRS-D444E.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AN 2690, AN2690, AN-2690, Antibiotic, Antifungal, inhibit, Kerydin, Inhibitor, Fungal, Tavaborole

Compound Identifiers

PubChem CID

11499245