Tat-βsyn-degron

SKU: orb3142320

Description

Tat-βsyn-degron is an α-synuclein (α-synuclein) knockdown peptide that efficiently degrades the α-synuclein protein via the proteasome pathway. It effectively reduces α-synuclein protein levels in primary rat cortical neuron cultures. In Parkinson's mouse toxicity models, Tat-βsyn-degron alleviates neuronal damage and motor dysfunction induced by Parkinsonian toxins.

Research Area

Signal Transduction

Key Properties

• Target: Others
• CAS Number: 2816095-52-8
• MW: 3146.67
• Formula: C₁₃₂H₂₃₇N₅₉O₃₁
• SMILES: [C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(NCC(O)=O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)C(C)C)=O)CC(C)C)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CCCCN)=O)CO)=O)=O)C(C)C)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others