TAT 14

SKU: orb1679244

Description

TAT-14 is a cell-permeable peptide activator of the Nrf2 transcription factor. It functions by disrupting the Keap1-Nrf2 interaction, leading to increased Nrf2 protein levels and subsequent anti-inflammatory activity, making it a valuable tool for studying oxidative stress and inflammation in both cellular and animal models.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• Target: Nrf2
• CAS Number: 1362661-34-4
• MW: 3173.59
• Formula: C₁₃₇H₂₃₀N₄₈O₃₉
• SMILES: CC[C@H](C)[C@@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)NC([C@H](CCC1)N1C([C@H](CC(C)C)NC([C@H](Cc1ccccc1)NC([C@H](CCC(O)=O)NC(CNC([C@H]([C@@H](C)O)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](Cc(cc1)ccc1O)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

60150581