AT 14 acetate

SKU: orb1296367

Description

TAT 14 acetate is a cell-permeable 14-mer peptide activator of the Nrf2 pathway. It functions by binding to Keap1, which stabilizes Nrf2 protein without affecting its mRNA, leading to upregulated antioxidant response element (ARE)-driven gene expression. This mechanism supports its application in researching oxidative stress and inflammation in both cellular and animal models.

Research Area

Immunology & Inflammation

Key Properties

• Target: Nrf2
• MW: 3233.64
• Purity: 96.90% (May vary between batches)
• Formula: C₁₃₉H₂₃₄N₄₈O₄₁
• SMILES: CC(O)=O.O=C(N)CC[C@@H](C(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H]1N(C([C@H](CC(C)C)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(O)=O)NC(CNC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CC3=CC=C(O)C=C3)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AT14 Acetate, AT-14 Acetate, AT 14 Acetate, AT 14 acetate, KEAP1-Nrf2

Compound Identifiers

PubChem CID

164185607