Tamsulosin hydrochloride

SKU: orb1227044

Description

Tamsulosin is a selective antagonist at alpha-1A and alpha-1B-adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck. At least three discrete alpha1-adrenoceptor subtypes have been identified: alpha-1A, alpha-1B and alpha-1D; their distribution differs between human organs and tissue. Approximately 70% of the alpha1-receptors in human prostate are of the alpha-1A subtype. Blockage of these receptors causes relaxation of smooth muscles in the bladder neck and prostate.

Key Properties

• CAS Number: 106463-17-6
• MW: 444.97
• Purity: >98% (HPLC)
• Formula: C₂₀H₂₉ClN₂O₅S
• SMILES: O=S(C1=CC=C(C[C@H](NCCOC2=CC=CC=C2OCC)C)C=C1)(N)=O.[H]Cl
• Target: Adrenergic Receptor
• Solubility: Water: 215.9 mg/L

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LY253351 | YM-12617-1

Quick Database Links

Gene Symbol

Adrenergic Receptor