Synephrine

SKU: orb1309115

Description

Synephrine

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 94-07-5
• MW: 167.21
• Purity: 99.63% (May vary between batches)
• Formula: C₉H₁₃NO₂
• SMILES: CNCC(O)c1ccc(O)cc1
• Target: Endogenous Metabolite|||Adrenergic Receptor
• Solubility: DMSO:83.33 mg/mL (498.36 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (19.74 mM);Ethanol:2 mg/mL (11.96 mM)

Bioactivity

• In Vivo:
  LD50: Mice >1000 mg/kg (s.c.)
• In Vitro:
  Synephrine is a compound commonly used for weight loss. Synephrine has gained significant popularity as an alternative to ephedrine. Products containing bitter orange or synephrine are suspected of causing adverse cardiovascular reactions. Synephrine can stimulate glucose consumption (Glut4-dependent glucose uptake) by stimulating AMPK activity, regardless of insulin-stimulated PI3 kinase-Akt activity in L6 skeletal muscle cells.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AdrenergicReceptor, Adrenergic Receptor, alkaloid, Beta Receptor, EndogenousMetabolite, Endogenous Metabolite, Inhibitor, inhibit, loss, Oxedrine, Synephrine, sympathomimetic, β-adrenergic, α-adrenergic, weight

Compound Identifiers

PubChem CID

7172