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Syk Inhibitor II hydrochloride

SKU: orb1685280

Description

Spleen tyrosine kinase (Syk) is a key signaling node for multiple inflammatory stimuli relevant to lupus. Studies in FcgRIIb-deficient models show Syk inhibition reduces inflammatory cytokine production and attenuates sepsis severity, highlighting its potential as a research target for autoimmune and inflammatory disease investigations.

Research Area

Cardiovascular Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2490508-82-0
MW376.77
Purity98.17% (May vary between batches)
FormulaC14H16ClF3N6O
SMILESO=C(C1=CN=C(NCCN)N=C1NC2=CC=CC(C(F)(F)F)=C2)N.[H]Cl
TargetOthers
SolubilityDMSO:55 mg/mL (145.98 mM)

Bioactivity

Target IC50
5-HT receptor:460 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Syk Inhibitor II Hydrochloride, Syk Inhibitor II hydrochloride

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 180.00
25 mg
$ 270.00
50 mg
$ 400.00
100 mg
$ 610.00
DispatchUsually dispatched within 5-10 working days
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