SuperKillerTRAIL, Soluble Recombinant Protein

• Catalog Number: orb1230076
• Category: Proteins
• Description: SuperKillerTRAIL, Soluble Recombinant Protein
• Target: TNFSF10
• Tag: His Tag
• Form/Appearance: Liquid
• Concentration: 0.5mg/ml
• Buffer/Preservatives: In 20mM HEPES, pH 7.4, 150mM NaCl, 0.005% Tween 20, 1% sucrose, 1mM DTT.
• Purity: >98% (SDS-PAGE). Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
• Protein Sequence: The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge.
• UniProt ID: P10148
• Application notes: This recombinant proteins is for research use only.
• Source: E. coli
• Biological Activity: Induces apoptosis at concentrations of >1ng/ml. Note: Does not require a cross-linking enhancer for its potent biological activity. Shows superior activity on human cell lines that require extensive cross-linking of TRAIL-Rs for killing (e.g. Jurkat).
• Storage: Once thawed it is recommended to prepare appropriate aliquots and to store them at -80˚°C.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Alternative names: TRAIL, Apo-2L, TNFSF10, CD253
• Research Area: Cancer Biology, Cell Biology, Immunology & Inflamm
• Note: For research use only
• NCBI: P50591
• Expiration Date: 6 months from date of receipt.