SuperKillerTRAIL, Soluble Recombinant Protein

• Catalog Number: orb1230075
• Category: Proteins
• Description: SuperKillerTRAIL, Soluble Recombinant Protein
• Target: Tnfsf10
• Tag: His Tag
• Form/Appearance: Liquid
• Concentration: 0.5mg/ml
• Buffer/Preservatives: In 20mM HEPES, pH 7.4, 300mM NaCl, 0.01% Tween 20, 1% sucrose, 1mM DTT.
• Purity: >95% (SDS-PAGE). Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
• Protein Sequence: The extracellular domain of mouse TRAIL (aa 99-291) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge.
• UniProt ID: P13236
• Application notes: This recombinant proteins is for research use only.
• Source: E. coli
• Biological Activity: Induces apoptosis at concentrations of >10ng/ml as tested on human tumor cells. This effect can be efficiently blocked by recombinant mouse TRAIL receptors. This protein does not require a cross-linker (enhancer) for its potent biological activity.
• Storage: Once thawed it is recommended to prepare appropriate aliquots and to store them at -80˚°C.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Alternative names: TRAIL, Apo-2L, TNFSF10, CD253
• Note: For research use only
• NCBI: P50592