Sucralose

SKU: orb1224662

Description

Sucralose is an artificial and noncaloric sweetener, not broken down by the body, so it is noncaloric.(In Vitro):The results show that Sucralose induces significant increased incidence of all hematopoietic neoplasias in male mice exposed to 2,000 (p≤0.01), and 16,000 ppm (p≤0.01), with a significant dose-related relationship (p≤0.01). Microscopically, most of the neoplasias among male mice treated with Sucralose at 2,000 to 16,000 ppm are leukemias involving lungs, liver, spleen, lymph nodes, and bone marrow with diffuse permeation of vessels and extensive infiltration of adjacent tissues.

Key Properties

• CAS Number: 56038-13-2
• MW: 397.63
• Purity: >98% (HPLC)
• Formula: C₁₂H₁₉Cl₃O₈
• SMILES: C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)CCl)O)O)CCl)O)O)Cl)O
• Target: Others
• Solubility: Water: 80 mg/mL (201.19 mM); DMSO: 80 mg/mL (201.19 mM)

Bioactivity

• In Vivo:
  The results show that Sucralose induces significant increased incidence of all hematopoietic neoplasias in male mice exposed to 2, 000 (p≤0.01), and 16, 000 ppm (p≤0.01), with a significant dose-related relationship (p≤0.01). Microscopically, most of the neoplasias among male mice treated with Sucralose at 2, 000 to 16, 000 ppm are leukemias involving lungs, liver, spleen, lymph nodes, and bone marrow with diffuse permeation of vessels and extensive infiltration of adjacent tissues.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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