STUB1 Rabbit mAb [KD Validated]

SKU: orb1950685

Description

E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90.

Images & Validation

• Tested Applications: FC, ICC, IP, WB
• Dilution range: WB 1:1000~1:5000 ICC/IF 1:50~1:200 IP 1:80 FC 1:50
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Recombinant
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human STUB1
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Disclaimer: For research use only

Alternative Names

STUB1; CHIP; HSPABP2; NY-CO-7; SDCCAG7; UBOX1;

All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature.

Western blot analysis of STUB1 expression in (1) HEK293 cell lysate; (2) Mouse brain lysate.

Quick Database Links

UniProt

Q9UNE7