STING antagonist 1

SKU: orb2646042

Description

STINGantagonist 1 (Compound 107) is a potent and selective STING inhibitor with an IC50 of 3.8 nM in biochemical assays and 31 nM in human whole blood. This cell-permeable tool compound is valuable for investigating STING-mediated signaling in autoimmune, inflammatory, and cancer research, both in vitro and in vivo.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Key Properties

• CAS Number: 3036981-21-9
• MW: 519.62
• Formula: C₃₁H₃₀FN₇
• SMILES: CN1C(=C(N=C1C=2C(CC)=NC=3C(C2)=CN(C)N3)C=4C=5C(=NN(C[C@H](F)C6=CC=CC=C6)C5)C=CC4)C7CC7
• Target: STING

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171534056