STAT5B (C) Antibody, Rabbit Polyclonal

• Catalog Number: orb67261
• Category: Antibodies
• Description: Rabbit polyclonal to STAT5B.Signal transducer and activator of transcription 5B (STAT5B) belongs to the transcription factor STATfamily. STAT5B carries out a dual function: signal transduction and activation of transcription.STAT5B is tyrosine phosphorylated in response to signaling via activated KIT, resulting in itstranslocation to the nucleus, where it binds to the GAS element in DNA and activates PRL-inducedtranscription. STAT5B mediates cellular responses to the cytokine KITLG/SCF and other growthfactors. Defects in STAT5B are the cause of growth hormone insensitivity with immunodeficiency(GHII).
• Clonality: Polyclonal
• Species/Host: Rabbit
• Conjugation: Unconjugated
• Reactivity: Human, Mouse
• Buffer/Preservatives: 0.01% NaN3
• Purity: Affinity purification
• Immunogen: C-terminal region of human STAT5B
• UniProt ID: P51692
• MW: 90
• Tested applications: WB
• Dilution range: WB:1:500-1:2000
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: anti-STAT5B antibody,anti-Signal transducer and ac
• Research Area: Epigenetics
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Jurkat(Lane1) and mouse thymus(Lane2) using STAT5B antibody