ST271

SKU: orb1302798

Description

ST271 is a potent and selective small molecule inhibitor of protein tyrosine kinases (PTKs). It is a valuable research tool for studying PTK signaling pathways in both cellular (in vitro) and animal (in vivo) models of cancer and other diseases.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 106392-48-7
• MW: 272.34
• Purity: 98.94% (May vary between batches)
• Formula: C₁₆H₂₀N₂O₂
• SMILES: CC(C)c1cc(\C=C(/C#N)C(N)=O)cc(C(C)C)c1O
• Target: Phospholipase|||Tyrosine Kinases
• Solubility: DMSO:50 mg/mL (183.59 mM)

Bioactivity

• Target IC50:
  PTK(PAF):9 μM|PTK(fMet-Leu-Phe):6.7μM
• In Vitro:
  The formation of inositol phosphates,which is induced by FcγRII cross-linking, is inhibited by ST271 (100 μM).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PTK, ST 271, ST271, ST-271, Phospholipase, TyrosineKinases, Tyrosine Kinases, inhibit, Inhibitor

Compound Identifiers

PubChem CID

6439072