Sphingosine-1-phosphate

SKU: orb3032925

Description

Sphingosine-1-phosphate (S1P) functions as a versatile signaling molecule, acting both intracellularly and extracellularly. Within cells, it serves as a secondary messenger, playing a key role in calcium ion (Ca²⁺) mobilization. Externally, S1P acts as a ligand, binding to and activating a range of G protein-coupled receptors, including S1P1-5 receptors as well as GPR3, GPR6, and GPR12. This bioactive lipid is synthesized from sphingomyelin and other membrane phospholipids, highlighting its importance as a critical mediator in various cellular processes.

Key Properties

• CAS Number: 26993-30-6
• MW: 379.47182
• Purity: >98%
• Formula: C₁₈H₃₈NO₅P
• SMILES: CCCCCCCCCCCCC/C=C/[C@H]([C@H](COP(=O)(O)O)N)O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only