Sphingosine-1-phosphate

SKU: orb1819284

Description

Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, and GPR12. As an intracellular second messenger, it mobilizes Ca2+ and acts as an extracellular ligand for G-protein coupled receptors. This important lipid mediator is generated from sphingosine or other membrane phospholipids.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	26993-30-6
MW	379.47
Purity	98.66%
Formula	C₁₈H₃₈NO₅P
SMILES	[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)(COP(=O)(O)O)N
Target	Endogenous Metabolite,LPL Receptor,S1P Receptor
Solubility	H2O:< 1 mg/mL (insoluble);NaOH:12.5 mg/mL (32.94 mM)

Storage & Handling

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Storage	store at low temperature,keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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S1P1, Sphingosine-1-phosphate (d18:1), Endogenous Metabolite, LPL Receptor

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Gene Symbol

Endogenous Metabolite,LPL Receptor,S1P Receptor

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