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SOS1 activator 1

SKU: orb1686839

Description

SOS1 activator 1 is a small molecule that potently activates the SOS1 guanine nucleotide exchange factor (Kd = 44 nM), promoting the exchange of GDP for GTP on RAS proteins. This tool compound is used in vitro and in vivo to investigate RAS signaling pathways in cancer research and cellular biology.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2245237-53-8
MW483.02
FormulaC26H32ClFN6
SMILESC(N1C(=NC=2C1=CC(Cl)=CC2N3CCN(C)CC3)N4CC5(C4)CNC5)C6=CC(C)=C(F)C(C)=C6
TargetRas,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information