PROTAC SOS1 degrader-8

SKU: orb2564655

Description

PROTA CSOS1 degrader-8 (Compd 1) is a SOS1-targeting PROTAC molecule. It facilitates the ubiquitination and degradation of SOS1, a key RAS activator, and is utilized in vitro and in vivo for investigating KRAS-driven cancer biology and targeted protein degradation strategies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 3036155-11-7
• MW: 914.54
• Formula: C₅₀H₆₀ClN₁₁O₄
• SMILES: N([C@H](C)C1=C(C)C(C#N)=CC=C1)C=2C3=C(C=NC(=C3)N4CCN(C(=O)C5CCN(CC6CCC7(CC6)CCN(C(=O)C8=CC(=C(Cl)C=C8)N9C(=O)NC(=O)CC9)CC7)CC5)CC4)C(C)=NN2
• Target: PROTACs,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171714344