Solasodine

SKU: orb1303271

Description

Solasodine is a steroidal alkaloid found in Solanaceae plants, noted for its selective cytotoxicity against cancer cell lines such as HeLa and U937. Research applications include investigating its mechanisms and potential in vitro and in vivo models for oncology and apoptosis studies.

Research Area

Cell Biology, Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 126-17-0
• MW: 413.64
• Purity: 99.94% (May vary between batches)
• Formula: C₂₇H₄₃NO₂
• SMILES: C[C@@H]1[C@]2(O[C@@]3([C@]1([C@]4(C)[C@@](C3)([C@]5([C@](CC4)([C@]6(C)C(=CC5)C[C@@H](O)CC6)[H])[H])[H])[H])[H])CC[C@@H](C)CN2
• Target: Apoptosis,MDM-2/p53,Antifungal,E1/E2/E3 Enzyme
• Solubility: DMSO:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• Target IC50:
  HeLa cells:12.17 ± 3.3 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

E3 ligating enzyme, E2 Enzyme, E2 conjugating enzyme, E2Enzyme, E3 Enzyme, E3Enzyme, E1/E2/E3 Enzyme, E1Enzyme, E1 activating enzyme, E1 Enzyme, doublecortin, alkaloid, anticancer, antiatherosclerotic, anti-inflammatory, Apoptosis, antifungal, Inhibitor, hypotensive, MDM-2/p53, Fungal, inhibit, Neuroprotective s, Solasodin, Solasodine, Solancarpidine, steroidal, Purapuridine, Ubiquitin conjugating enzyme, Ubiquitin ligase, Ubiquitin activating enzyme, βIII-tubulin

Compound Identifiers

PubChem CID

442985