Sodium oleate

SKU: orb1693779

Description

Sodium oleate, the sodium salt of the abundant monounsaturated oleic acid, is a known activator of the Na+/K+ ATPase enzyme. It is used in biochemical research to study ion transport mechanisms, membrane biophysics, and lipid metabolism in both cellular and isolated enzyme systems.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 143-19-1
• MW: 304.44
• Purity: 95.45% (May vary between batches)
• Formula: C₁₈H₃₃NaO₂
• SMILES: [Na+].CCCCCCCC\C=C/CCCCCCCC([O-])=O
• Target: ATPase
• Solubility: DMSO:Insoluble;Ethanol:PBS(pH 7.2) (1:1):0.5 mg/mL (1.64 mM);Ethanol:1.5 mg/mL (4.93 mM);H2O:1.25 mg/mL (4.11 mM)

Bioactivity

• In Vitro:
  Sodium oleate is the most common monounsaturated fatty acids (FA) in human adipocytes and other tissues. Sodium oleate prompts cell proliferation and migration in high metastatic cancer cells via enhancing β-oxidation mediated by AMPK activation. Sodium oleate inhibits cancer cell growth and survival in low metastatic carcinoma cells, such as gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Na+/K+ ATPase, Oleic acid sodium, Oleic acid sodium salt, cis-9-Octadecenoic acid sodium, cis-9-Octadecenoic acid sodium salt, Sodium oleate

Compound Identifiers

PubChem CID

23665730