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SIRT5 inhibitor 8

SKU: orb2278353

Description

SIRT5 inhibitor 8 (compound 10) is a substrate-competitive inhibitor with moderate selectivity and an IC50 of 5.38 µM against SIRT5. It is a useful chemical probe for investigating the role of SIRT5 in cancer metabolism and tumorigenesis in both cellular and animal model studies.

Research Area

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3054055-22-7
MW501
Purity99.56% (May vary between batches)
FormulaC22H25ClN8O2S
SMILESO=C(O)CCNC(=S)NCCCNC=1N=C(N=C(N1)NC=2C=CC=CC2Cl)NC=3C=CC=CC3
TargetSirtuin

Bioactivity

Target IC50
SIRT5: 5.38 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 540.00
5 mg
$ 1,170.00
10 mg
$ 1,570.00
25 mg
$ 2,320.00
50 mg
$ 2,800.00
DispatchUsually dispatched within 5-10 working days
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