Sintilimab Antibody

SKU: orb1694625

Description

Sintilimab (IBI308) is a humanized IgG4 anti-PD-1 monoclonal antibody that blocks PD-1/PD-L1/2 interactions to restore anti-tumor T-cell activity. It is used clinically in combination therapies for cancers including classical Hodgkin's lymphoma, non-small cell lung cancer, and esophageal carcinoma, and is widely applied in immuno-oncology research for in vitro and in vivo experimental studies.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• Antibody Type: Inhibitor Antibody
• Clonality: Monoclonal
• Target: PD-1/PD-L1
• Molecular Weight: 143.78 kDa
• Purity: >95.0% (May vary between batches)
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Concentration: 3.67 mg/mL
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PD-1, PD-1/PD-L1, PD1/PDL1, PD1, PDL1, PD-L1, IBI308, IBI-308, IBI 308, anti-PD-1, Sintilimab (anti-PD-1), Sintilimab

Quick Database Links

Gene Symbol

PD-1/PD-L1