Silybin A

SKU: orb1307850

Description

Silibinin

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 22888-70-6
• MW: 482.44
• Purity: 97.98% (May vary between batches)
• Formula: C₂₅H₂₂O₁₀
• SMILES: C(O)[C@@H]1[C@H](OC=2C(O1)=CC=C(C2)[C@H]3OC=4C(C(=O)[C@@H]3O)=C(O)C=C(O)C4)C5=CC(OC)=C(O)C=C5
• Target: ROS,Autophagy,Reactive Oxygen Species
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.84 mM);DMSO:260 mg/mL (538.93 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• In Vivo:
  Research indicates that silibinin protects liver cells from toxin-induced damage, serving a hepatoprotective function. In vitro, studies demonstrate that silibinin exhibits anticancer effects against a variety of human cancer cells, including prostate cancer cells, estrogen-dependent/independent breast cancer cells, colorectal cancer cells, cervical cancer cells, and both small and non-small cell lung cancer cells. Silibinin is a mixture of the diastereoisomers silibinin A and silibinin B, approximately in a 1:1 ratio.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Autophagy, Reactive Oxygen Species, ReactiveOxygenSpecies, Silibinin A, Silibinin, Silybin, Silymarin I

Compound Identifiers

PubChem CID

31553