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SHP2 IN-1

SKU: orb1708529

Description

SHP2 IN-1 is a potent and selective allosteric inhibitor of the protein tyrosine phosphatase SHP2 (PTPN11), exhibiting an IC50 of 3 nM. This compound is a valuable research tool for investigating SHP2-dependent signaling pathways in cancer and developmental disorders, applicable in both cellular and biochemical assays.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number1801764-90-8
MW441.38
FormulaC18H22Cl2N6OS
SMILESN[C@H]1C2(CCN(CC2)C3=NC(N)=C(SC=4C(Cl)=C(Cl)N=CC4)N=C3)C[C@H](O)C1
TargetPhosphatase,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information