SHP2/HDAC-IN-1

SKU: orb1744631

Description

SHP2/HDAC-IN-1 is a potent dual allosteric inhibitor of SHP2 (IC50=20.4 nM) and HDAC1 (IC50=25.3 nM). It demonstrates potential for cancer immunotherapy research by activating T-cells, enhancing antigen presentation, and promoting cytokine secretion in preclinical studies.

Research Area

Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 2831230-38-5
• MW: 660.59
• Formula: C₃₄H₃₅Cl₂N₇O₃
• SMILES: ClC1=C(C=CC=C1Cl)C=2C(N)=NC(=CN2)N3CCC(NCC4=CC=C(C(NCC5=CC=C(/C=C/C(NO)=O)C=C5)=O)C=C4)(C)CC3
• Target: Others,Phosphatase,HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165412812