SHC3 (C) Antibody, Rabbit Polyclonal

SKU: orb67257

Description

Rabbit polyclonal to SHC3.SHC-transforming protein 3 (SHC3) is a signaling adapter that couples activated growth factorreceptors to signaling pathway in neurons. SHC3 is involved in the signal transduction pathways ofneurotrophin-activated Trk receptors in cortical neurons. SHC3 can bind activated TrkB receptorfollowing the stimulation with brain-derived neurotrophic factor , which is the most abundantneurotrophin in the brain.

Research Area

Epigenetics, Neuroscience

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:500-1:2000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of human SHC3
• Molecular Weight: 64
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-SHC3 antibody,anti-SHCtransforming protein 3 antibody,anti-Neuronal Shc antibody,anti-NShc antibody,anti-Protein Rai antibody,anti-SHCtransforming protein C antibody,anti-Src homology 2 domaincontainingtransforming protein C3 antibody,anti-SH2 domain protein C3 antibody,anti-NSHC antibody,anti-SHCC antibody

Western blot analysis of total cell extracts from mouse brain using SHC3 antibody

Quick Database Links

UniProt

Q92529