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Seribantumab Antibody

SKU: orb1980652

Description

Seribantumab (MM-121) is a humanized anti-HER3 monoclonal antibody that blocks NRG1-mediated signaling, suppressing growth in breast and lung cancer models with NRG1 alterations and inducing apoptosis in specific cell lines. It has been investigated in both in vitro and in vivo studies for targeting HER3-dependent cancers.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
ClonalityMonoclonal
TargetApoptosis,HER,EGFR
Molecular Weight143.14 kDa
Purity96.26% (May vary between batches)
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration9.41 mg/mL
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

MM121, MM-121, SAR256212, SAR-256212

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

Select a size below

1 mg
$ 120.00
5 mg
$ 280.00
10 mg
$ 430.00
25 mg
$ 670.00
50 mg
$ 930.00
Free Secondary Antibody (20 ul)0/0

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DispatchUsually dispatched within 5-10 working days
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