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SDC1 Antibody / Syndecan-1
Catalog Number: orb2636113
| Catalog Number | orb2636113 |
|---|---|
| Category | Antibodies |
| Description | CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinoma. |
| Clonality | Recombinant |
| Species/Host | Mouse |
| Isotype | Mouse IgG1, kappa |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | A recombinant fragment (within amino acids 200-300) of human CD138 protein was used as the immunogen for the recombinant SDC1 antibody. |
| UniProt ID | P18827 |
| Tested applications | FACS, IHC-P |
| Dilution range | Flow cytometry: 1-2ug/million cells,Immunohistochemistry (FFPE): 1-2ug/ml |
| Application notes | Optimal dilution of the recombinant SDC1 antibody should be determined by the researcher. |
| Antibody Type | Primary Antibody |
| Clone Number | rSDC1/6866 |
| Formula | 1 mg/ml in 1X PBS; BSA free, sodium azide free |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Hazard Information | This recombinant SDC1 antibody is available for research use only. |
| Note | For research use only |
SDS-PAGE analysis of purified, BSA-free recombinant SDC1 antibody (clone rSDC1/6866) as confirmation of integrity and purity.
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