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SCL-1

SKU: orb3136809

Description

SCL-1 is an orally active anti-PD-1/PD-L1 inhibitor that disrupts the interaction between PD-1 and PD-L1. It enhances the numbers of T cells, B cells, and natural killer cells. SCL-1 exhibits potent tumor growth inhibitory effects by inducing effector T cells within the tumor and upregulating the expression of long non-coding RNAs as neoantigens, thereby activating cytotoxic T lymphocytes. SCL-1 is applicable in cancer research, including studies on triple-negative breast cancer.

Images & Validation

Key Properties

CAS Number1061105-16-5
MW396.41
FormulaC18H23F3N6O
SMILESO=C(N1CCCCC1C)C2CCN(C3=NN4C(=NN=C4C(F)(F)F)C=C3)CC2
TargetPD-1/PD-L1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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SCL-1 (orb3136809)

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