Schisandrin A

SKU: orb1698887

Description

Schisandrin A is a bioactive lignan from Schisandra chinensis that potently inhibits CYP3A enzyme activity, with an IC50 of 6.60 µM and a Ki of 5.83 µM. This inhibitor is a valuable research tool for investigating drug metabolism, pharmacokinetic interactions, and cytochrome P450 function in both in vitro and in vivo studies.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 61281-38-7
• MW: 416.51
• Purity: 99.21% (May vary between batches)
• Formula: C₂₄H₃₂O₆
• SMILES: COc1cc2C[C@H](C)[C@H](C)Cc3cc(OC)c(OC)c(OC)c3-c2c(OC)c1OC
• Target: Virus Protease,Cytochromes P450,Autophagy
• Solubility: DMSO:83.33 mg/mL (200.07 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.8 mM)

Bioactivity

• Target IC50:
  CYP3A:6.60 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Wuweizisu-A, Schizandrin A, Schizandrin-A, Schisandrin A, Virus Protease, VirusProtease, CYPs, CYP3A, Cytochrome P450, Deoxyschizandrin, Autophagy, Inhibitor, inhibit

Compound Identifiers

PubChem CID

155256