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SARS-CoV-2 (COVID-19) Nucleocapsid protein

SARS-CoV-2 (COVID-19) Nucleocapsid protein

Catalog Number: orb669292

DispatchUsually dispatched within 5-10 working days
$ 302,591.00
Catalog Numberorb669292
CategoryProteins
DescriptionNucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
ReactivityVirus
TagC-6×His
Form/AppearanceLiquid
Purity95%
ConjugationUnconjugated
MW47.3 kDa
TargetNucleocapsid protein
Protein SequenceYP_009724397.2
SourceSARS-CoV-2 Nucleocapsid protein, His Tag (orb669292) is expressed from human 293 cells (HEK293).
Expression SystemHEK293
Endotoxins1.0 EU per μg
NCBIYP_009724397.2
Storage-70℃
Buffer/Preservatives10 mM PB, 150 mM NaCl, pH7.4
Alternative namesNucleocapsid protein,NP,Protein N
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NoteFor research use only
Application notesThis protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.3 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date6 months from date of receipt.
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