SALL2 (N) Antibody, Rabbit Polyclonal

SKU: orb131889

Description

Rabbit polyclonal to SALL2. SALL proteins are C2H2 zinc-finger transcription factors in which the zinc-finger motifs are distributed over the entire protein. They contain glutamine-, proline-and alanine-rich sequences typical of transcriptional activators or repressors. Four members of the human family have been identified, SALL 1-4. Although human SALL-1, -3 and -4 are associated with malformation syndromes, SALL2 is not. Rather, SALL2 is a potential tumour suppressor. The SALL2 gene maps to 14q11.1-13, a region associated with loss of heterozygosity in half of human ovarian cancers. SALL2 is well expressed in ovarian epithelial cells but depleted in ovarian carcinoma cells. Expression of SALL2 in ovarian carcinoma cells inhibits DNA synthesis and colony formation, increases expression of p21WAF1/CIP1 and reduces tumorigenicity.

Research Area

Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:3000
• Reactivity: Human, Mouse
• Application Notes:
  WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; ; Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human SALL2.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human SALL2
• Molecular Weight: 105
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Concentration: 100 μg/ml BSA
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti Sal-like protein 2 antibody, anti Zinc finger protein 795 antibody, anti Zinc finger protein SALL2 antibody, anti Zinc finger protein Spalt-2 antibody, anti Sal-2 antibody, anti hSal2 antibody, anti KIAA0360 antibody, anti SAL2 antibody, anti ZNF795 antibody

Quick Database Links

UniProt

Q9Y467